PharmOptima provides
consulting and laboratory services
As experts at drug discovery,
we help clients create data packages to maximize the value
of their intellectual property. Our expertise
includes:
- In vivo ADME;
establishing bioanalytical assays using HPLC/MS-MS and
other methods, pharmacokinetic studies, PK/PD analyses,
and GLP sample analysis
- In vitro ADME including
microsomal and cellular metabolic profiling, isozyme
characterization, p450 inhibition, and protein binding
- In vivo proof of concept
testing and model development to confirm drug delivery,
efficacy, and tolerance plus next steps in the discovery
process
- Establishing and
optimizing assays for high throughput screening, HTS data
analysis, and designing/implementing secondary assays
PharmOptima’s
scientists have a successful R&D track record in
cardiovascular, CNS, cancer, dermatology, and infectious
diseases; over 300 cumulative years experience; 325
publications; and inventors on 14 patents. Clients
save money and time by identifying problems with their drug
candidates early, before costly animal safety and first in
man testing.
