PharmOptima Services

PharmOptima focuses on the mid to late phases of drug discovery between target selection and choice of compounds, helping clients select the best candidates to accelerate development and increase chances for clinical success. We also provide consultation and laboratory support for target selection and HTS assays. Our clients save money and time by identifying problems with their drug candidates early, before costly animal safety and first in man testing.

Click here to learn more about PharmOptima's enhanced Drug Discovery Process.

PharmOptima's Core R&D Competencies:

Experts in preclinical PK, PK/PD assessments and ADME for IND submissions, plus additional ADME services for NDA filings Broad experience in drug discovery, in vivo model development, pharmacology, and PD/PK studies Expertise in developing and validating analytical assays and analyzing compounds in test articles and biological matrices PharmOptima’s analytical labs are GLP compliant Proven track records in infectious diseases, cardiovascular, CNS, cancer, and dermatology Scientists knowledgeable in the requirements for successful drug discovery and registration Scientists with hundreds of years of cumulative experience in big Pharma, over 300 scientific publications, thousands of technical reports, and inventors on 14 patents

PharmOptima Develops Customized Solutions for Your Drug Discovery, Formulation and in vivo Profiling Problems:

Assay design and development to optimize high throughput screening Consultation, contract laboratory work and data analysis HTS strategies and analysis Biochemical mechanism of action determinations Proof of concept testing for pharmacologic efficacy, tolerance and ADME In vitro and in vivo ADME Ocular PK Bioanalytical assays including GLP regulated assays Integrated prospective research strategies to optimize your chances of success Complete drug discovery service in one CRO

PharmOptima's Services Add Value to the Drug Discovery Process:

Optimizing screening assays, insuring identification of authentic leads Early identification of a compound's biochemical mechanism of action Providing initial proof of concept testing in animals for compound bioavailability, efficacy, tolerance and ADME