SERVICES
Our ophthalmic services begin, run and conclude with a high level of technical expertise.
From specialized ocular dosing by trained scientists, to the precise dissection of specific ocular tissues by our specialists, followed by exacting sample processing and bioanalysis by PharmOptima’s experienced staff; we stand out against the large CRO model of generalized necropsy technicians and crash & shoot discovery bioanalysis. Our bioanalytical team has extensive experience processing, homogenizing and extracting ocular fluids and tissues. We have developed LC-MS/MS methods for hundreds of compounds.
What we can do for you:
- validate bioanalytical methods following current FDA Crystal City and OECD guidances
- perform cross validations for additional species and matrices
- assay plasma and dosing solutions from regulated animal safety studies (i.e. GLP) and clinical trials
- assay metabolism of drugs/prodrugs in ocular tissue